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Hallmarks of HIV-1 pathogenesis are modulated by Nef’s Secretion Modification Region
CD4(+) T cell depletion and immune activation are hallmarks of HIV infection. Despite extensive studies, the mechanisms underlying immune modulation remain elusive. HIV-1 Nef protein is secreted in exosomes from infected cells and is abundant in the plasma of HIV+ individuals. Exosomal Nef (exNef) w...
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| 出版年: | J AIDS Clin Res |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4625552/ https://ncbi.nlm.nih.gov/pubmed/26523240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-6113.1000476 |
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