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Hallmarks of HIV-1 pathogenesis are modulated by Nef’s Secretion Modification Region

CD4(+) T cell depletion and immune activation are hallmarks of HIV infection. Despite extensive studies, the mechanisms underlying immune modulation remain elusive. HIV-1 Nef protein is secreted in exosomes from infected cells and is abundant in the plasma of HIV+ individuals. Exosomal Nef (exNef) w...

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Dades bibliogràfiques
Publicat a:J AIDS Clin Res
Autors principals: Konadu, Kateena Addae, Anderson, Joseph S, Huang, Ming-Bo, Ali, Syed A, Powell, Michael D, Villinger, Francois, Bond, Vincent C
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625552/
https://ncbi.nlm.nih.gov/pubmed/26523240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-6113.1000476
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