Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin

BACKGROUND: Myxoid liposarcoma is a histological subtype of liposarcoma particularly sensitive to trabectedin. In clinical use this drug does not cause cumulative toxicity, allowing prolonged treatment, generally until disease progression. No other effective therapies are available for trabectedin-r...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Cancer
Prif Awduron: Bello, Ezia, Brich, Silvia, Craparotta, Ilaria, Mannarino, Laura, Ballabio, Sara, Gatta, Raffaella, Marchini, Sergio, Carrassa, Laura, Matteo, Cristina, Sanfilippo, Roberta, Gronchi, Alessandro, Casali, Paolo Giovanni, Pilotti, Silvana, D’Incalci, Maurizio, Frapolli, Roberta
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738121/
https://ncbi.nlm.nih.gov/pubmed/31409911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0550-2
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