Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin

BACKGROUND: Myxoid liposarcoma is a histological subtype of liposarcoma particularly sensitive to trabectedin. In clinical use this drug does not cause cumulative toxicity, allowing prolonged treatment, generally until disease progression. No other effective therapies are available for trabectedin-r...

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Udgivet i:Br J Cancer
Main Authors: Bello, Ezia, Brich, Silvia, Craparotta, Ilaria, Mannarino, Laura, Ballabio, Sara, Gatta, Raffaella, Marchini, Sergio, Carrassa, Laura, Matteo, Cristina, Sanfilippo, Roberta, Gronchi, Alessandro, Casali, Paolo Giovanni, Pilotti, Silvana, D’Incalci, Maurizio, Frapolli, Roberta
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738121/
https://ncbi.nlm.nih.gov/pubmed/31409911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0550-2
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