Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin

BACKGROUND: Myxoid liposarcoma is a histological subtype of liposarcoma particularly sensitive to trabectedin. In clinical use this drug does not cause cumulative toxicity, allowing prolonged treatment, generally until disease progression. No other effective therapies are available for trabectedin-r...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Bello, Ezia, Brich, Silvia, Craparotta, Ilaria, Mannarino, Laura, Ballabio, Sara, Gatta, Raffaella, Marchini, Sergio, Carrassa, Laura, Matteo, Cristina, Sanfilippo, Roberta, Gronchi, Alessandro, Casali, Paolo Giovanni, Pilotti, Silvana, D’Incalci, Maurizio, Frapolli, Roberta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738121/
https://ncbi.nlm.nih.gov/pubmed/31409911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0550-2
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