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The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance

BACKGROUND: Radiotherapy (RT) is a highly effective multimodal nonsurgical treatment that is essential for patients with advanced colorectal cancer (CRC). Nevertheless, cell subpopulations displaying intrinsic radioresistance survive after RT. The reactivation of their proliferation and successful c...

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Foilsithe in:J Exp Clin Cancer Res
Main Authors: Park, So-Yeon, Lee, Choong-Jae, Choi, Jang-Hyun, Kim, Jee-Heun, Kim, Ji-Won, Kim, Ji-Young, Nam, Jeong-Seok
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737692/
https://ncbi.nlm.nih.gov/pubmed/31511084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1405-7
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