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The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance

BACKGROUND: Radiotherapy (RT) is a highly effective multimodal nonsurgical treatment that is essential for patients with advanced colorectal cancer (CRC). Nevertheless, cell subpopulations displaying intrinsic radioresistance survive after RT. The reactivation of their proliferation and successful c...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Park, So-Yeon, Lee, Choong-Jae, Choi, Jang-Hyun, Kim, Jee-Heun, Kim, Ji-Won, Kim, Ji-Young, Nam, Jeong-Seok
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737692/
https://ncbi.nlm.nih.gov/pubmed/31511084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1405-7
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