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The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance
BACKGROUND: Radiotherapy (RT) is a highly effective multimodal nonsurgical treatment that is essential for patients with advanced colorectal cancer (CRC). Nevertheless, cell subpopulations displaying intrinsic radioresistance survive after RT. The reactivation of their proliferation and successful c...
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| Publicado no: | J Exp Clin Cancer Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6737692/ https://ncbi.nlm.nih.gov/pubmed/31511084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1405-7 |
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