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Selective deletion of ENTPD1/CD39 in macrophages exacerbates biliary fibrosis in a mouse model of sclerosing cholangitis

Purinergic signaling is important in the activation and differentiation of macrophages, which play divergent roles in the pathophysiology of liver fibrosis. The ectonucleotidase CD39 is known to modulate the immunoregulatory phenotype of macrophages, but whether this specifically impacts cholestatic...

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Publicat a:Purinergic Signal
Autors principals: Rothweiler, Sonja, Feldbrügge, Linda, Jiang, Zhenghui Gordon, Csizmadia, Eva, Longhi, Maria Serena, Vaid, Kahini, Enjyoji, Keiichi, Popov, Yury V., Robson, Simon C.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737175/
https://ncbi.nlm.nih.gov/pubmed/31243614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-019-09664-3
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