Deletion of Cd39/Entpd1 Results in Hepatic Insulin Resistance

OBJECTIVE—Extracellular nucleotides are important mediators of inflammatory responses and could also impact metabolic homeostasis. Type 2 purinergic (P2) receptors bind extracellular nucleotides and are expressed by major peripheral tissues responsible for glucose homeostasis. CD39/ENTPD1 is the dom...

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Main Authors: Enjyoji, Keiichi, Kotani, Ko, Thukral, Chandrashekar, Blumel, Benjamin, Sun, Xiaofeng, Wu, Yan, Imai, Masato, Friedman, David, Csizmadia, Eva, Bleibel, Wissam, Kahn, Barbara B., Robson, Simon C.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2008
Teme:
Metabolism
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518482/
https://ncbi.nlm.nih.gov/pubmed/18567823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1265
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