Disordered Purinergic Signaling Inhibits Pathological Angiogenesis in Cd39/Entpd1-Null Mice

CD39/ecto-nucleoside triphosphate diphosphohydrolase-type-1 (ENTPD1) is the dominant vascular ecto-nucleotidase that catalyzes the phosphohydrolysis of extracellular nucleotides in the blood and extracellular space. This ecto-enzymatic process modulates endothelial cell, leukocyte, and platelet puri...

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Hlavní autoři: Jackson, Shaun W., Hoshi, Tomokazu, Wu, Yan, Sun, Xiaofeng, Enjyoji, Keiichi, Cszimadia, Eva, Sundberg, Christian, Robson, Simon C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2007
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988887/
https://ncbi.nlm.nih.gov/pubmed/17823293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070190
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