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Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/Entpd1 null mice
Liver cancer is associated with chronic inflammation, which is linked to immune dysregulation, disordered metabolism and aberrant cell proliferation. CD39/ENTPD1 is an ectonucleotidase that regulates extracellular nucleotide/nucleoside concentrations by scavenging nucleotides to ultimately generate...
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| 主要な著者: | , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505255/ https://ncbi.nlm.nih.gov/pubmed/22859060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25989 |
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