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RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution
Holliday junctions (HJs) are four-way DNA structures that occur in DNA repair by homologous recombination. Specialized nucleases, termed resolvases, remove (i.e., resolve) HJs. The bacterial protein RuvC is a canonical resolvase that introduces two symmetric cuts into the HJ. For complete resolution...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6736871/ https://ncbi.nlm.nih.gov/pubmed/31506434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11900-8 |
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