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Crystal structure of RuvC resolvase in complex with Holliday junction substrate

The key intermediate in genetic recombination is the Holliday junction (HJ), a four-way DNA structure. At the end of recombination, HJs are cleaved by specific nucleases called resolvases. In Gram-negative bacteria, this cleavage is performed by RuvC, a dimeric endonuclease that belongs to the retro...

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Библиографические подробности
Главные авторы: Górecka, Karolina M., Komorowska, Weronika, Nowotny, Marcin
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834835/
https://ncbi.nlm.nih.gov/pubmed/23980027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt769
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