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An agonist of the MscL channel affects multiple bacterial species and increases membrane permeability and potency of common antibiotics
The bacterial MscL channel normally functions as an emergency release valve discharging cytoplasmic solutes upon osmotic stress. The channel opens and passes molecules up to 30 A and its pore is the largest of any gated channel. Opening the MscL pore inappropriately is detrimental to the bacterial c...
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| Gepubliceerd in: | Mol Microbiol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6736685/ https://ncbi.nlm.nih.gov/pubmed/31177589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14325 |
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