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Streptomycin potency is dependent on MscL channel expression

The antibiotic streptomycin is widely used in the treatment of microbial infections. The primary mechanism of action is inhibition of translation by binding to the ribosome, but how it enters the bacterial cell is unclear. Early in the study of this antibiotic, a mysterious streptomycin-induced K(+)...

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Bibliografiske detaljer
Main Authors: Iscla, Irene, Wray, Robin, Wei, Shuguang, Posner, Bruce, Blount, Paul
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161981/
https://ncbi.nlm.nih.gov/pubmed/25205267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5891
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