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On the Structure of the N-Terminal Domain of the MscL Channel: Helical Bundle or Membrane Interface

The mechanosensitive channel of large conductance, MscL, serves as a biological emergency release valve protecting bacteria from acute osmotic downshock and is to date the best characterized mechanosensitive channel. A well-recognized and supported model for Escherichia coli MscL gating proposes tha...

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Autori principali: Iscla, Irene, Wray, Robin, Blount, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517020/
https://ncbi.nlm.nih.gov/pubmed/18515388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.127423
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