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Defining the Physical Gate of a Mechanosensitive Channel, MscL, by Engineering Metal-Binding Sites
The mechanosensitive channel of large conductance, MscL, of Escherichia coli is one of the best-studied mechanosensitive proteins. Although the structure of the closed or “nearly-closed” state of the Mycobacterium tuberculosis ortholog has been solved and mechanisms of gating have been proposed, the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304787/ https://ncbi.nlm.nih.gov/pubmed/15339809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.049833 |
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