Atovaquone-Proguanil in Combination With Artesunate to Treat Multidrug-Resistant P. falciparum Malaria in Cambodia: An Open-Label Randomized Trial

BACKGROUND: Recent artemisinin-combination therapy failures in Cambodia prompted a search for alternatives. Atovaquone‐proguanil (AP), a safe, effective treatment for multidrug-resistant Plasmodium falciparum (P.f.), previously demonstrated additive effects in combination with artesunate (AS). METHO...

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Vydáno v:Open Forum Infect Dis
Hlavní autoři: Wojnarski, Mariusz, Lon, Chanthap, Vanachayangkul, Pattaraporn, Gosi, Panita, Sok, Somethy, Rachmat, Agus, Harrison, Dustin, Berjohn, Catherine M, Spring, Michele, Chaoratanakawee, Suwanna, Ittiverakul, Mali, Buathong, Nillawan, Chann, Soklyda, Wongarunkochakorn, Saowaluk, Waltmann, Andreea, Kuntawunginn, Worachet, Fukuda, Mark M, Burkly, Hana, Heang, Vireak, Heng, Thay Keang, Kong, Nareth, Boonchan, Threechada, Chum, Bolin, Smith, Philip, Vaughn, Andrew, Prom, Satharath, Lin, Jessica, Lek, Dysoley, Saunders, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
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Major Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736354/
https://ncbi.nlm.nih.gov/pubmed/31660398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz314
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