Atovaquone-Proguanil Remains a Potential Stopgap Therapy for Multidrug-Resistant Plasmodium falciparum in Areas along the Thai-Cambodian Border

Our recent report of dihydroartemisinin-piperaquine failure to treat Plasmodium falciparum infections in Cambodia adds new urgency to the search for alternative treatments. Despite dihydroartemisinin-piperaquine failure, and higher piperaquine 50% inhibitory concentrations (IC(50)s) following reanal...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Saunders, David L., Chaorattanakawee, Suwanna, Gosi, Panita, Lanteri, Charlotte, Somethy, Sok, Kuntawunginn, Worachet, Ittiverakul, Mali, Chann, Soklyda, Gregory, Carrie, Chuor, Char Meng, Prom, Satharath, Spring, Michele D., Lon, Chanthap
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Clinical Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775999/
https://ncbi.nlm.nih.gov/pubmed/26711753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02302-15
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