Atovaquone-Proguanil in Combination With Artesunate to Treat Multidrug-Resistant P. falciparum Malaria in Cambodia: An Open-Label Randomized Trial

BACKGROUND: Recent artemisinin-combination therapy failures in Cambodia prompted a search for alternatives. Atovaquone‐proguanil (AP), a safe, effective treatment for multidrug-resistant Plasmodium falciparum (P.f.), previously demonstrated additive effects in combination with artesunate (AS). METHO...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Wojnarski, Mariusz, Lon, Chanthap, Vanachayangkul, Pattaraporn, Gosi, Panita, Sok, Somethy, Rachmat, Agus, Harrison, Dustin, Berjohn, Catherine M, Spring, Michele, Chaoratanakawee, Suwanna, Ittiverakul, Mali, Buathong, Nillawan, Chann, Soklyda, Wongarunkochakorn, Saowaluk, Waltmann, Andreea, Kuntawunginn, Worachet, Fukuda, Mark M, Burkly, Hana, Heang, Vireak, Heng, Thay Keang, Kong, Nareth, Boonchan, Threechada, Chum, Bolin, Smith, Philip, Vaughn, Andrew, Prom, Satharath, Lin, Jessica, Lek, Dysoley, Saunders, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736354/
https://ncbi.nlm.nih.gov/pubmed/31660398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz314
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