Piperaquine Population Pharmacokinetics and Cardiac Safety in Cambodia

Despite the rising rates of resistance to dihydroartemisinin-piperaquine (DP), DP remains a first-line therapy for uncomplicated malaria in many parts of Cambodia. While DP is generally well tolerated as a 3-day DP (3DP) regimen, compressed 2-day DP (2DP) regimens were associated with treatment-limi...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Vanachayangkul, Pattaraporn, Lon, Chanthap, Spring, Michele, Sok, Sommethy, Ta-aksorn, Winita, Kodchakorn, Chanikarn, Pann, Sut-Thang, Chann, Soklyda, Ittiverakul, Mali, Sriwichai, Sabaithip, Buathong, Nillawan, Kuntawunginn, Worachet, So, Mary, Youdaline, Theng, Milner, Erin, Wojnarski, Mariusz, Lanteri, Charlotte, Manning, Jessica, Prom, Satharath, Haigney, Mark, Cantilena, Louis, Saunders, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404605/
https://ncbi.nlm.nih.gov/pubmed/28193647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02000-16
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