Prevalence of CYP2D6 Genotypes and Predicted Phenotypes in a Cohort of Cambodians at High Risk for Infections with Plasmodium vivax

Clinical failure of primaquine (PQ) has been demonstrated in people with CYP450 2D6 genetic polymorphisms that result in reduced or no enzyme activity. The distribution of CYP2D6 genotypes and predicted phenotypes in the Cambodian population is not well described. Surveys in other Asian countries ha...

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Publicado no:Am J Trop Med Hyg
Main Authors: Spring, Michele D., Lon, Chanthap, Sok, Somethy, Sea, Darapiseth, Wojnarski, Mariusz, Chann, Soklyda, Kuntawunginn, Worachet, Kheang Heng, Thay, Nou, Samon, Arsanok, Montri, Sriwichai, Sabaithip, Vanachayangkul, Pattaraporn, Lin, Jessica T., Manning, Jessica E., Jongsakul, Krisada, Pichyangkul, Sathit, Satharath, Prom, Smith, Philip L., Dysoley, Lek, Saunders, David L., Waters, Norman C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410472/
https://ncbi.nlm.nih.gov/pubmed/32394887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.20-0061
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