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Prevalence of CYP2D6 Genotypes and Predicted Phenotypes in a Cohort of Cambodians at High Risk for Infections with Plasmodium vivax

Clinical failure of primaquine (PQ) has been demonstrated in people with CYP450 2D6 genetic polymorphisms that result in reduced or no enzyme activity. The distribution of CYP2D6 genotypes and predicted phenotypes in the Cambodian population is not well described. Surveys in other Asian countries ha...

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Detaylı Bibliyografya
Yayımlandı:Am J Trop Med Hyg
Asıl Yazarlar: Spring, Michele D., Lon, Chanthap, Sok, Somethy, Sea, Darapiseth, Wojnarski, Mariusz, Chann, Soklyda, Kuntawunginn, Worachet, Kheang Heng, Thay, Nou, Samon, Arsanok, Montri, Sriwichai, Sabaithip, Vanachayangkul, Pattaraporn, Lin, Jessica T., Manning, Jessica E., Jongsakul, Krisada, Pichyangkul, Sathit, Satharath, Prom, Smith, Philip L., Dysoley, Lek, Saunders, David L., Waters, Norman C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society of Tropical Medicine and Hygiene 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410472/
https://ncbi.nlm.nih.gov/pubmed/32394887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.20-0061
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