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The glucocorticoid receptor DNA-binding domain recognizes RNA hairpin structures with high affinity
The glucocorticoid receptor (GR) binds the noncoding RNA Gas5 via its DNA-binding domain (DBD) with functional implications in pro-apoptosis signaling. Here, we report a comprehensive in vitro binding study where we have determined that GR-DBD is a robust structure-specific RNA-binding domain. GR-DB...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6735959/ https://ncbi.nlm.nih.gov/pubmed/31147715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz486 |
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