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PopCluster: an algorithm to identify genetic variants with ethnicity-dependent effects

MOTIVATION: Over the last decade, more diverse populations have been included in genome-wide association studies. If a genetic variant has a varying effect on a phenotype in different populations, genome-wide association studies applied to a dataset as a whole may not pinpoint such differences. It i...

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Vydáno v:Bioinformatics
Hlavní autoři: Gurinovich, Anastasia, Bae, Harold, Farrell, John J, Andersen, Stacy L, Monti, Stefano, Puca, Annibale, Atzmon, Gil, Barzilai, Nir, Perls, Thomas T, Sebastiani, Paola
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735784/
https://ncbi.nlm.nih.gov/pubmed/30624692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz017
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