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Inhibition of p53 inhibitors: progress, challenges and perspectives
p53 is the major tumor suppressor and the most frequently inactivated gene in cancer. p53 could be disabled either by mutations or by upstream negative regulators, including, but not limited to MDM2 and MDMX. p53 activity is required for the prevention as well as for the eradication of cancers. Rest...
Guardat en:
| Publicat a: | J Mol Cell Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6735775/ https://ncbi.nlm.nih.gov/pubmed/31310659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz075 |
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