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p53 CRISPR Deletion Affects DNA Structure and Nuclear Architecture
The TP53 gene is a key tumor suppressor. Although the tumor suppressor p53 was one of the first to be characterized as a transcription factor, with its main function potentiated by its interaction with DNA, there are still many unresolved questions about its mechanism of action. Here, we demonstrate...
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| Udgivet i: | J Clin Med |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7073688/ https://ncbi.nlm.nih.gov/pubmed/32098416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9020598 |
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