The synergistic antileukemic effects of eltrombopag and decitabine in myeloid leukemia cells

BACKGROUND: Hypomethylating agents (HMAs), such as decitabine (DAC), are currently used as first-line therapy for patients with high-risk myelodysplastic syndromes (MDS) and acute myelogenous leukemia (AML) not eligible for standard chemotherapies. Exacerbation of thrombocytopenia is one of the prev...

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Publicado en:Cancer Manag Res
Autores principales: Shi, Mingyue, Xu, Fangfang, Yang, Xiawan, Bai, Yanliang, Niu, Junwei, Drokow, Emmanuel Kwateng, Chen, Mingyi, Chen, Yuqing, Sun, Kai
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove 2019
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735651/
https://ncbi.nlm.nih.gov/pubmed/31564981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S213931
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