Nalaganje...
Role of the Carboxylate in Enzyme-Catalyzed Decarboxylation of Orotidine 5′-Monophosphate: Transition State Stabilization Dominates Over Ground State Destabilization
[Image: see text] Kinetic parameters k(ex) (s(–1)) and k(ex)/K(d) (M(–1) s(–1)) are reported for exchange for deuterium in D(2)O of the C-6 hydrogen of 5-fluororotidine 5′-monophosphate (FUMP) catalyzed by the Q215A, Y217F, and Q215A/Y217F variants of yeast orotidine 5′-monophosphate decarboxylase (...
Shranjeno v:
| izdano v: | J Am Chem Soc |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2019
|
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6735427/ https://ncbi.nlm.nih.gov/pubmed/31365243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b04823 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|