Učitavanje...
Sphingosine -1 Phosphate Receptor-1 signaling maintains endothelial cell barrier function and protects against immune complex-induced vascular injury
OBJECTIVE: Immune complex (IC) deposition activates neutrophils (PMN), increases vascular permeability and leads to organ damage in SLE and RA. The bioactive lipid sphingosine-1-phosphate (S1P), acting via S1P receptor 1 (S1P(1)), is a key regulator of endothelial cell (EC) barrier function. We hypo...
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| Izdano u: | Arthritis Rheumatol |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6734184/ https://ncbi.nlm.nih.gov/pubmed/29781582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40558 |
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