A Novel Gain-of-Function Nav1.9 Mutation in a Child With Episodic Pain

Voltage-gated sodium channel Nav1.9 is a threshold channel that regulates action potential firing. Nav1.9 is preferentially expressed in myenteric neurons, and small-diameter dorsal root ganglion (DRG) and trigeminal ganglion neurons including nociceptors. Recent studies have demonstrated a monogeni...

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Bibliografiska uppgifter
I publikationen:Front Neurosci
Huvudupphovsmän: Huang, Jianying, Estacion, Mark, Zhao, Peng, Dib-Hajj, Fadia B., Schulman, Betsy, Abicht, Angela, Kurth, Ingo, Brockmann, Knut, Waxman, Stephen G., Dib-Hajj, Sulayman D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733892/
https://ncbi.nlm.nih.gov/pubmed/31551682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00918
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