A Gain-of-Function Mutation in Nav1.6 in a Case of Trigeminal Neuralgia

Idiopathic trigeminal neuralgia (TN) is a debilitating pain disorder characterized by episodic unilateral facial pain along the territory of branches of the trigeminal nerve. Human pain disorders, but not TN, have been linked to gain-of-function mutations in peripheral voltage-gated sodium channels...

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Publicado en:Mol Med
Autores principales: Tanaka, Brian S, Zhao, Peng, Dib-Hajj, Fadia B, Morisset, Valerie, Tate, Simon, Waxman, Stephen G, Dib-Hajj, Sulayman D
Formato: Artigo
Lenguaje:Inglês
Publicado: Feinstein Institute for Medical Research 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023517/
https://ncbi.nlm.nih.gov/pubmed/27496104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00131
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