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Trigeminal Neuralgia TRPM8 Mutation: Enhanced Activation, Basal [Ca(2+)](i) and Menthol Response
OBJECTIVE: To assess the functional effects of a variant, c.89 G > A (p.Arg30Gln), in the transient receptor potential melastatin 8 (TRPM8) cold-sensing, nonselective cation channel, which we have previously identified in a patient with familial trigeminal neuralgia. METHODS: We carried out Ca(2+...
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| Publicado no: | Neurol Genet |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wolters Kluwer
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8105906/ https://ncbi.nlm.nih.gov/pubmed/33977138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000550 |
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