Response of high-risk MDS to azacitidine and lenalidomide is impacted by baseline and acquired mutations in a cluster of three inositide-specific genes

Specific myeloid-related and inositide-specific gene mutations can be linked to myelodysplastic syndromes (MDS) pathogenesis and therapy. Here, 44 higher-risk MDS patients were treated with azacitidine and lenalidomide and mutations analyses were performed at baseline and during the therapy. Results...

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書誌詳細
出版年:Leukemia
主要な著者: Follo, Matilde Y., Pellagatti, Andrea, Armstrong, Richard N., Ratti, Stefano, Mongiorgi, Sara, De Fanti, Sara, Bochicchio, Maria Teresa, Russo, Domenico, Gobbi, Marco, Miglino, Maurizio, Parisi, Sarah, Martinelli, Giovanni, Cavo, Michele, Luiselli, Donata, McCubrey, James A., Suh, Pann-Ghill, Manzoli, Lucia, Boultwood, Jacqueline, Finelli, Carlo, Cocco, Lucio
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733710/
https://ncbi.nlm.nih.gov/pubmed/30787430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0416-x
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