Structure and dynamics of Helicobacter pylori nickel-chaperone HypA: an integrated approach using NMR spectroscopy, functional assays and computational tools

Helicobacter pylori HypA (HpHypA) is a metallochaperone necessary for maturation of [Ni,Fe]-hydrogenase and urease, the enzymes required for colonization and survival of H. pylori in the gastric mucosa. HpHypA contains a structural Zn(II) site and a unique Ni(II) binding site at the N-terminus. X-ra...

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Bibliografiset tiedot
Julkaisussa:J Biol Inorg Chem
Päätekijät: Spronk, Chris A. E. M., Żerko, Szymon, Górka, Michał, Koźmiński, Wiktor, Bardiaux, Benjamin, Zambelli, Barbara, Musiani, Francesco, Piccioli, Mario, Basak, Priyanka, Blum, Faith C., Johnson, Ryan C., Hu, Heidi, Merrell, D. Scott, Maroney, Michael, Ciurli, Stefano
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733409/
https://ncbi.nlm.nih.gov/pubmed/30264175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-018-1616-y
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