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Structure-function analyses of metal-binding sites of HypA reveal residues important for hydrogenase maturation in Helicobacter pylori

The nickel-containing enzymes of Helicobacter pylori, urease and hydrogenase, are essential for efficient colonization in the human stomach. The insertion of nickel into urease and hydrogenase is mediated by the accessory protein HypA. HypA contains an N-terminal nickel-binding site and a dynamic st...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Blum, Faith C., Hu, Heidi Q., Servetas, Stephanie L., Benoit, Stéphane L., Maier, Robert J., Maroney, Michael J., Merrell, D. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557546/
https://ncbi.nlm.nih.gov/pubmed/28809946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183260
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