Structure-function analyses of metal-binding sites of HypA reveal residues important for hydrogenase maturation in Helicobacter pylori

The nickel-containing enzymes of Helicobacter pylori, urease and hydrogenase, are essential for efficient colonization in the human stomach. The insertion of nickel into urease and hydrogenase is mediated by the accessory protein HypA. HypA contains an N-terminal nickel-binding site and a dynamic st...

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發表在:PLoS One
Main Authors: Blum, Faith C., Hu, Heidi Q., Servetas, Stephanie L., Benoit, Stéphane L., Maier, Robert J., Maroney, Michael J., Merrell, D. Scott
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557546/
https://ncbi.nlm.nih.gov/pubmed/28809946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183260
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