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CD8αα homodimers function as a coreceptor for KIR3DL1

Cluster of differentiation 8 (CD8) is a cell surface glycoprotein, which is expressed as 2 forms, αα homodimer or αβ heterodimer. Peptide-loaded major histocompatibility complex class I (pMHC-I) molecules are major ligands for both forms of CD8. CD8αβ is a coreceptor for the T cell receptor (TCR) an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Geng, Jie, Raghavan, Malini
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731649/
https://ncbi.nlm.nih.gov/pubmed/31420518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905943116
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