NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts

Natural Killer (NK) cell education, which requires the engagement of inhibitory NK cell receptors (iNKRs) by their ligands, is important for generating self-tolerant functional NK cells. While the potency of NK cell education is directly related to their functional potential upon stimulation with HL...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Isitman, Gamze, Tremblay-McLean, Alexandra, Lisovsky, Irene, Bruneau, Julie, Lebouché, Bertrand, Routy, Jean-Pierre, Bernard, Nicole F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061331/
https://ncbi.nlm.nih.gov/pubmed/27732638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164517
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