Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody‐dependent (AD) NK cell activation and ADCC

The engagement of activating NK receptors (aNKR) stimulates NK cell activity, provided that interactions between inhibitory NK receptors (iNKR) with their HLA ligands do not override them. Abs bound to target cells can also activate NK cells by engaging the CD16 aNKR. NK cell education status is an...

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Veröffentlicht in:J Leukoc Biol
Hauptverfasser: Lisovsky, Irene, Kant, Sanket, Tremblay‐McLean, Alexandra, Isitman, Gamze, Kiani, Zahra, Dupuy, Franck P., Gilbert, Louise, Bruneau, Julie, Shoukry, Naglaa H., Lebouché, Bertrand, Bernard, Nicole F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Host Defense & Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916277/
https://ncbi.nlm.nih.gov/pubmed/30698860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4A0617-242RRR
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