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The murine CD94/NKG2 ligand, Qa-1(b), is a high-affinity, functional ligand for the CD8αα homodimer

The immune co-receptor CD8 molecule (CD8) has two subunits, CD8α and CD8β, which can assemble into homo or heterodimers. Nonclassical (class-Ib) major histocompatibility complex (MHC) molecules (MHC-Ibs) have recently been identified as ligands for the CD8αα homodimer. This was demonstrated by the o...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Goodall, Katharine Jennifer, Nguyen, Angela, McKenzie, Craig, Eckle, Sidonia Barbara Guiomar, Sullivan, Lucy Catherine, Andrews, Daniel Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062157/
https://ncbi.nlm.nih.gov/pubmed/31992596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010509
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