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Empty conformers of HLA-B preferentially bind CD8 and regulate CD8(+) T cell function
When complexed with antigenic peptides, human leukocyte antigen (HLA) class I (HLA-I) molecules initiate CD8(+) T cell responses via interaction with the T cell receptor (TCR) and co-receptor CD8. Peptides are generally critical for the stable cell surface expression of HLA-I molecules. However, for...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5990358/ https://ncbi.nlm.nih.gov/pubmed/29741477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36341 |
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