Using Transcriptomic Hidden Variables to Infer Context-Specific Genotype Effects in the Brain

Deciphering the environmental contexts at which genetic effects are most prominent is central for making full use of GWAS results in follow-up experiment design and treatment development. However, measuring a large number of environmental factors at high granularity might not always be feasible. Ins...

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Publicado en:Am J Hum Genet
Autores principales: Ng, Bernard, Casazza, William, Patrick, Ellis, Tasaki, Shinya, Novakovsky, Gherman, Felsky, Daniel, Ma, Yiyi, Bennett, David A., Gaiteri, Chris, De Jager, Philip L., Mostafavi, Sara
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731371/
https://ncbi.nlm.nih.gov/pubmed/31447098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.07.016
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