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Multi-omic Directed Networks Describe Features of Gene Regulation in Aged Brains and Expand the Set of Genes Driving Cognitive Decline

Multiple aspects of molecular regulation, including genetics, epigenetics, and mRNA collectively influence the development of age-related neurologic diseases. Therefore, with the ultimate goal of understanding molecular systems associated with cognitive decline, we infer directed interactions among...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Tasaki, Shinya, Gaiteri, Chris, Mostafavi, Sara, Yu, Lei, Wang, Yanling, De Jager, Philip L., Bennett, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095043/
https://ncbi.nlm.nih.gov/pubmed/30140277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00294
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