Functional disease architectures reveal unique biological role of transposable elements

Transposable elements (TE) comprise roughly half of the human genome. Though initially derided as junk DNA, they have been widely hypothesized to contribute to the evolution of gene regulation. However, the contribution of TE to the genetic architecture of diseases remains unknown. Here, we analyze...

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發表在:Nat Commun
Main Authors: Hormozdiari, Farhad, van de Geijn, Bryce, Nasser, Joseph, Weissbrod, Omer, Gazal, Steven, Ju, Chelsea J. -T., Connor, Luke O’, Hujoel, Margaux L. A., Engreitz, Jesse, Hormozdiari, Fereydoun, Price, Alkes L.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731302/
https://ncbi.nlm.nih.gov/pubmed/31492842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11957-5
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