Functional disease architectures reveal unique biological role of transposable elements

Transposable elements (TE) comprise roughly half of the human genome. Though initially derided as junk DNA, they have been widely hypothesized to contribute to the evolution of gene regulation. However, the contribution of TE to the genetic architecture of diseases remains unknown. Here, we analyze...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Hormozdiari, Farhad, van de Geijn, Bryce, Nasser, Joseph, Weissbrod, Omer, Gazal, Steven, Ju, Chelsea J. -T., Connor, Luke O’, Hujoel, Margaux L. A., Engreitz, Jesse, Hormozdiari, Fereydoun, Price, Alkes L.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731302/
https://ncbi.nlm.nih.gov/pubmed/31492842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11957-5
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