Enhanced Potency of GalNAc-Conjugated Antisense Oligonucleotides in Hepatocellular Cancer Models

Antisense oligonucleotides (ASOs) are a novel therapeutic approach to target difficult-to-drug protein classes by targeting their corresponding mRNAs. Significantly enhanced ASO activity has been achieved by the targeted delivery of ASOs to selected tissues. One example is the targeted delivery of A...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther
Egile Nagusiak: Kim, Youngsoo, Jo, Minji, Schmidt, Joanna, Luo, Xiaolin, Prakash, Thazha P., Zhou, Tianyuan, Klein, Stephanie, Xiao, Xiaokun, Post, Noah, Yin, Zhengfeng, MacLeod, A. Robert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2019
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731179/
https://ncbi.nlm.nih.gov/pubmed/31303442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.06.009
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