Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers

BACKGROUND AND PURPOSE: The objective of this study was to longitudinally investigate the trajectory of change in (1)H MRS measurements in asymptomatic MAPT mutation carriers who became symptomatic during follow‐up, and to determine the time at which the neurochemical alterations accelerated during...

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Dades bibliogràfiques
Publicat a:J Neuroimaging
Autors principals: Chen, Qin, Boeve, Bradley F., Tosakulwong, Nirubol, Lesnick, Timothy, Brushaber, Danielle, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Haley, Dana, Gunter, Jeffrey L., Graff‐Radford, Jonathan, Jones, David, Knopman, David, Graff‐Radford, Neill, Kraft, Ruth, Lapid, Maria, Rademakers, Rosa, Wszolek, Zbigniew K., Rosen, Howie, Boxer, Adam L., Kantarci, Kejal
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731148/
https://ncbi.nlm.nih.gov/pubmed/31173437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jon.12642
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