Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers

BACKGROUND AND PURPOSE: The objective of this study was to longitudinally investigate the trajectory of change in (1)H MRS measurements in asymptomatic MAPT mutation carriers who became symptomatic during follow‐up, and to determine the time at which the neurochemical alterations accelerated during...

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Detaylı Bibliyografya
Yayımlandı:J Neuroimaging
Asıl Yazarlar: Chen, Qin, Boeve, Bradley F., Tosakulwong, Nirubol, Lesnick, Timothy, Brushaber, Danielle, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Haley, Dana, Gunter, Jeffrey L., Graff‐Radford, Jonathan, Jones, David, Knopman, David, Graff‐Radford, Neill, Kraft, Ruth, Lapid, Maria, Rademakers, Rosa, Wszolek, Zbigniew K., Rosen, Howie, Boxer, Adam L., Kantarci, Kejal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731148/
https://ncbi.nlm.nih.gov/pubmed/31173437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jon.12642
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