In vivo (18)F-AV-1451 tau PET signal in MAPT mutation carriers varies by expected tau isoforms

OBJECTIVE: To evaluate (18)F-AV-1451 tau PET binding among microtubule-associated protein tau (MAPT) mutation carriers. METHODS: Using a case-control study, we quantitatively and qualitatively compared tau PET scans in 10 symptomatic and 3 asymptomatic MAPT mutation carriers (n = 13, age range 42–67...

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Xehetasun bibliografikoak
Argitaratua izan da:Neurology
Egile Nagusiak: Jones, David T., Knopman, David S., Graff-Radford, Jonathan, Syrjanen, Jeremy A., Senjem, Matthew L., Schwarz, Christopher G., Dheel, Christina, Wszolek, Zbigniew, Rademakers, Rosa, Kantarci, Kejal, Petersen, Ronald C., Jack, Clifford R., Lowe, Val J., Boeve, Bradley F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Lippincott Williams & Wilkins 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858948/
https://ncbi.nlm.nih.gov/pubmed/29440563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000005117
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