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Palladium-Catalyzed Enantioselective Alkenylation of Enelactams Using a Relay Heck Strategy

In this report, we describe a palladium-catalyzed redox relay Heck process to access optically active alkenylated α,β-unsaturated lactams. Under mild reaction conditions, electron-deficient alkenyl triflates and electron-rich alkenyl iodonium salts undergo enantioselective and site-selective couplin...

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Pubblicato in:Chemistry
Autori principali: Yuan, Qianjia, Sigman, Matthew S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731067/
https://ncbi.nlm.nih.gov/pubmed/31216370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201902813
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